Couples requiring embryo donation, undergo the preparation involved in a IVF cycle for a transfer and choose a healthy female donor as well as a healthy male donor. After which they are fertilised into embryos and transferred to the female recipient.
Embryo donation allows mother candidate to experience the feeling of pregnancy. In addition it offers couples the chance to experience the excitement involved in pregnancy and the bonding with the child and shared enthusiasm for the couple.
About Embryo Donation
- Couples who cannot produce viable sperm and oocytes;
- Couples with genetic disorders;
- Couples who after repeated attempts have been unable to develop a good quality embryo with their own sperm and egg;
- Couples who have experienced repeated unsuccessful IVF treatment.
The evaluation of the mother to be, in terms of both obstetrics and general health status is performed in detail as she is the main focus with treatment. Blood values and hormone levels are examined, in necessary cases, a medicated uterus film (Hysterosalpingography – HSG) should be checked in order to make sure the uterus is viable for pregnancy.
Preparation of treatment begins on day 2 or 3 of the menstrual cycle, (if menopausal then can directly begin). Preparation entails a series of vitamins to be taken i.e. Omega fish oil, Pre natal vitamins (containing folic acid) and Oestrogen tablets. Oestrogen tablets are taken so the endometrial lining (womb lining) is encouraged to thicken. The tablets are taken continuously over a 14 day period and after a series of trans-vaginal ultrasounds to ensure the endometrium is suitable, progesterone pessaries are introduced and the transfer takes place either 3-5days. In total there is a 3 week wait for the transfer of the embryo(s).
We find that the most important stage of donation treatment is the selection process of choosing the right donor. We are aware of the sensitivity surrounding this matter and how important it is to our patients.
Donor selection in our centre is evaluated in accordance to the guidelines issued by internationally respected reproductive medicine associations ESHRE and ASRM and many more.
We are one of few centres that also genetically evaluate our donors to see if they are carriers of any genetic diseases they may be unaware of. Today, we can perform the screening of over 230 genetic diseases of our donors via Recombine testing, which is only performed in our centre in Cyprus. Many IVF and donation centres serving in the region declare that they perform genetic screening tests (thalassemia, cystic fibrosis, etc.), which are recommended to be performed within the framework of common European standards in terms of common genetic diseases. Although these tests are expressed as genetic screening tests, they are blood tests rather than an examination in the gene level. Thus, they are not the test that can give a clear answer to the questions, which are the most commonly asked by treated couples;
“How safe are the eggs I received? Can an unknown genetic disease pass from the donor to our child? How good are egg donors examined for possible genetic diseases?”
Another of the most important features that differentiates us is. Thanks to being the first centre in Cyprus and over 20-years of experience, we have the most powerful donor pool in terms of diversity and number, in which you can choose the features such as physical characteristics, psychological characteristics, educational level and ethnicity as you wish.
We have the luxury of being selective when selecting our donors, as we are the centre of Cyprus with a vast donor pool. We accept our donors after passing and qualifying within the framework of strict rules up to sociocultural characteristics, occupation, external appearance, private life not only according to medicinal properties.
General selection and evaluation
In egg donation treatment, the candidates that will make egg donation (donor) are first evaluated in terms of ensuring high pregnancy success in the treatment. At this stage, it is essential that the age of the candidate is in the range of 18-30 years. The second stage is passed due to the provision of the criteria such as the lack of any general health problems / complaint / bad habits, the presence of a balanced spiritual nature, being able to comply with the instructions given to her during treatment.
Based on recent events we must alter the age of our donors
Medical examination and evaluation
Donor candidates are questioned and undergo the necessary examination that meets the general criteria, the examination consists of a trans-vaginal scan that is able to check the ovaries as well as for any cysts, polyps, uterine fibroids etc.
Examination in terms of sexually transmitted infectious diseases and serological examination are carried out as well.
As stated in the practice guidelines of for reproductive medicine associations, routine examination of the donor in terms of blood-borne and sexually transmitted diseases (HIV, hepatitis, syphilis, etc.) are checked and the evaluation of candidates is thorough and we are sure that they do not carry risk to begin the donation program. In this regard, all these examination are carried out over the donors in our centre.
Genetic examination (routine examination/advanced examinations)
At this stage, the donor candidates are screened by performing general routine tests (karyotype analysis, cystic fibrosis, thalassemia carrier tests, etc.) and it is determined whether they carry a defect in their chromosome or gene level that could risk transferring to an unborn baby. Although only karyotype analysis and a few rare genetic disease trait was examined in the standard donor selection and screening performed up to today, it is possible to screen the donor candidates in suitable conditions in terms of over 200 genetic diseases via a blood test called RECOMBINE in our clinic.
Evaluation of the donor according to the physical/mental/education etc. features
A candidate that successfully passed the blood, genetic and physical examinations stated above, are then evaluated and questioned in detail, at this stage they are evaluated in terms of certain physical characteristics (height, weight, hair colour, eye colour, body type, sporting activities, etc.), mental (active, outward oriented, curious, excited, positive, hobbies, etc.), educational status (college/graduate education completed, etc.) etc. Each of the parameters in question at this stage is listed so that it can be screened in accordance with the recipient’s request and can choose a suitable donor for her.
Special requests (if any) specified by the recipient
In some special cases, the recipient may have specific requests other than the general selection criteria mentioned above (a certain place of birth, body features, special artistic talent, etc.). Although we have a large selection of donors, recipients’ have to understand that matching a donor to their specific needs can take longer than the normal selection process.
Please click to browse our donors using a simplified form of our special program.